Article
Identifying Susceptibility Genes and Shared Genetic Architecture for Longevity and Muscle Weakness.
Journal of cachexia, sarcopenia and muscle - 1 Feb 2026
Lin Yilong, Zhang Yun, Lin Shengjie, Wang Songsong, Que Zhiqiang, Zhang Yue, She Jing, Zhao Ruidan, Chen Jiawei, Qiu Anqi, Wu Shinan, Yang Ruiqin, Zhang Liyi, Yang Qingmo
Abstract excerpt
BACKGROUND: Longevity and muscle strength are heritable traits, and age-related muscle weakness is a major contributor to disability in older adults. However, the susceptibility genes and shared genetic mechanisms underlying lifespan and sarcopenia remain unclear. This study aimed to identify genes associated with longevity and muscle weakness and to characterize their shared genetic architecture. METHODS: We...
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