Article

Germline <i>ERBB3</i> mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis

2020-05-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Lung cancer is the commonest cause of cancer deaths worldwide. Although strongly associated with smoking, predisposition to lung cancer is also heritable with multiple common risk variants identified. Rarely, dominantly inherited non-small-cell lung cancer (NSCLC) has been reported due to somatic mutations in EGFR/ErbB1 and ERBB2. <h4>Methods</h4> Germline exome sequencin...

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Literature Corpus work: f4ceefd9-fe41-54fc-b7c2-365ad9aa3f76
DOI: 10.1101/2020.05.29.122796

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