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Article

HER3 expression and MEK activation in non-small-cell lung carcinoma

9 Apr 2021

Abstract excerpt

Aim: We explore HER3 expression in lung adenocarcinoma (adeno-NSCLC) and identify potential mechanisms of HER3 expression. Materials & methods: Tumor samples from 45 patients with adeno-NSCLC were analyzed. HER3 and HER2 expression were identified using immunohistochemistry and bioinformatic interrogation of The Cancer Genome Atlas (TCGA). Results: HER3 was highly expressed in 42.2% of cases. ERBB3 copy number...

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PMID: 34084213
DOI: 10.2217/lmt-2020-0031

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