Article

RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity

2024-03-25

Abstract excerpt

<h4>ABSTRACT</h4> The cellular plasticity of neuroblastoma is defined by a mixture of two major cell states, adrenergic (ADRN) and mesenchymal (MES), which may contribute to therapy resistance. However, how neuroblastoma cells switch cellular states during therapy remains largely unknown and how to eradicate neuroblastoma regardless of their cell states is a clinical challenge. To better understand the lineage sw...

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Literature Corpus work: f4b6b2bd-8899-5284-b9bc-43e48d8b19d2
DOI: 10.1101/2024.03.21.586157

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