Article

Cell lineage as a predictor of immune response in neuroblastoma

2021-01-30

Abstract excerpt

<h4>SUMMARY</h4> Immunotherapy for patients with neuroblastoma has met with limited success, partly due to an incomplete understanding of the mechanisms underlying immune responsiveness in this clinically and genetically heterogenic tumor. Here, we undertook an unbiased analysis using dimension reduction and UMAP visualization of transcriptional signatures derived from 498 primary neuroblastoma tumors. Four disti...

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Literature Corpus work: 2fe33078-69a5-5477-bd5c-eb530f6b21a7
DOI: 10.1101/2021.01.29.428154

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