Article
A renal clearable fluorogenic probe for in vivo detection of cellular senescence
2021-04-23
Abstract excerpt
There is a growing need for non-invasive, cheap, and versatile diagnostic methods and the development of low-cost point-of-care assays constitutes a potential solution. Here, we describe the design of a renal clearable fluorogenic probe ( Cy7Gal ) which produces a fluorogenic signal readable in the urine. The Cy7Gal probe is applied to the detection of the burden of senescence in several in vivo models. The probe...
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Identifiers and source
- Literature Corpus work
- f4a0cf4a-2e02-58fb-a80f-762f86ecbb3b
- DOI
- 10.21203/rs.3.rs-418261/v1
