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Article

Senescence-Associated β-Galactosidase Detection in Pathology

25 Sept 2022

Abstract excerpt

Activity of β-galactosidase at pH 6 is a classic maker of senescence in cellular biology. Cellular senescence, a state of highly stable cell cycle arrest, is often compared to apoptosis as an intrinsic tumor suppression mechanism. It is also thought that SA-β-gal is crucial in malignant cell transformation. High levels of senescence-associated β-galactosidase (SA-β-gal) can be found in cancer and benign lesions...

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Share to Advanced biosensing and bioanalysis techniques
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Share to Telomeres, Telomerase, and Senescence

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PMID: 36291998
DOI: 10.3390/diagnostics12102309

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