Article

Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

2022-01-04

Abstract excerpt

<h4>Summary</h4> Rhabdomyosarcomas (RMS) are mesenchyme-derived tumors and the most common childhood soft tissue sarcomas. Treatment is intense, with a nevertheless poor prognosis for high-risk patients. Discovery of new therapies would benefit from additional preclinical models. Here we describe the generation of a collection of pediatric RMS tumor organoid (tumoroid) models comprising all major subtypes. For ag...

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Literature Corpus work: f4987a90-5b9a-5248-96e7-6170b9e0c636
DOI: 10.1101/2022.01.03.474504

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