Article

Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma

2023-10-17

Abstract excerpt

<h4>SUMMARY</h4> Rhabdomyosarcoma (RMS) is a pediatric tumor that resembles undifferentiated muscle cells; yet the extent to which cell state heterogeneity and molecular features are shared with human development have not been fully ascribed. Here, we report a single-cell/nucleus RNA sequencing atlas derived from 72 datasets that includes patient tumors, patient-derived xenografts, primary in vitro cultures, and...

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Literature Corpus work: 452941ca-d497-5490-bccd-a06f6adb5162
DOI: 10.1101/2023.10.13.562224

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