Article

RNA-multi-omics in single cells reveal rhythmical RNA reshaping during human and mouse oocyte maturation

2025-01-07

Abstract excerpt

<title>Abstract</title> <p>Most RNA molecules are present with m<sup>7</sup>G-cap and Poly(A)-tail at the 5’ or 3’ termini. However, existing next-generation sequencing (NGS) based single-cell RNA-sequencing methods are limited in capturing complete RNA molecules, often missing critical information at the 5’ or 3’ termini. Here, we developed a method named Cap to Tail sequencing application (C2T-APP) and simultan...

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Literature Corpus work: f4936ef3-ca24-530d-bb8d-56e4274be444
DOI: 10.21203/rs.3.rs-5212370/v1

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