Back to search

Article

<i>ZNF827</i> pleiotropic cardiovascular risk locus involves regulation by Nuclear factor-1

2024-01-24

Abstract excerpt

<h4>Introduction</h4> SCAD (spontaneous coronary artery dissection) is a form of myocardial infarction that disproportionately affects young women. SCAD is caused by the formation of a hematoma within coronary artery wall, resulting in its blockage. Sixteen SCAD susceptibility loci are currently known, including ZNF827 gene locus on chromosome 4. Several common genetic variations within ZNF827 are also linked t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f490c0d8-eb94-55ac-84c4-2fa7e2faf372
DOI
10.1101/2024.01.23.576845
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>ZNF827</i> pleiotropic cardiovascular risk locus involves regulation by Nuclear factor-1DOI 10.1101/2024.01.23.576845
ZNF827 pleiotropic cardiovascular risk locus involves regulation by nuclear factor-1.Semantic proximity
Multi-trait and Gene-Based Analyses Identify Genetic Variants Associated with Spontaneous Coronary Artery DissectionSemantic proximity
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarctionSemantic proximity
Comprehensive identification of coronary artery disease-associated variants regulating vascular smooth muscle cell gene expressionSemantic proximity
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseasesSemantic proximity
Genetic regulation of human aortic smooth muscle cell gene expression and splicing predict causal coronary artery disease genesSemantic proximity
Genome-wide association meta-analysis of spontaneous coronary artery dissection reveals common variants and genes related to artery integrity and tissue-mediated coagulationSemantic proximity
An interplay of non-coding RNAs regulates CDH13 expression and affects endothelial function and coronary artery disease riskSemantic proximity
Genetic Association of Circulating Proteins and Gene Transcripts With Spontaneous Coronary Artery Dissection.Semantic proximity
Regulatory mechanisms in multiple vascular diseases locus <i>LRP1</i> involve repression by SNAIL and extracellular matrix remodelingSemantic proximity
Post-genome-wide association study dissects genetic vulnerability and risk gene expression of Sjögren’s disease for cardiovascular diseaseSemantic proximity
Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing.Semantic proximity
Select a neighboring publication to make it the new centre.