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Integrative analysis of GTEx data reveals that systemic transcriptomes correlate with human spermatogenic dysfunction

2025-11-20

Abstract excerpt

Declining of male fertility may stem from intrinsic testicular dysfunction or systemic influences from other tissues. However, beyond the hypothalamic-pituitary-testis axis, little is known about which organs interact with the testes or whether they affect spermatogenic capacity. To investigate this, we analyzed GTEx open-access data, comparing transcriptomic profiles across various tissues in men with high and lo...

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Literature Corpus work
f48d12e6-6ab2-5dbb-82ed-e04fa8ca0e60
DOI
10.1101/2025.11.19.689370
Open publication

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Integrative analysis of GTEx data reveals that systemic transcriptomes correlate with human spermatogenic dysfunctionDOI 10.1101/2025.11.19.689370
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