Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets

19 Aug 2020

Abstract excerpt

BACKGROUND: The development of a safe, effective, reversible, non-hormonal contraceptive method for men has been an ongoing effort for the past few decades. However, despite significant progress on elucidating the function of key proteins involved in reproduction, understanding male reproductive physiology is limited by incomplete information on the genes expressed in reproductive tissues, and no contraceptive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32814578
DOI: 10.1186/s12915-020-00826-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasetsPMID 32814578Read ↗

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†Semantic proximity Read ↗

Multiomics analysis of male infertilitySemantic proximity Read ↗

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecunditySemantic proximity Read ↗

Novel Genes of the Male Reproductive System: Potential Roles in Male Reproduction and as Non‐hormonal Male Contraceptive TargetsSemantic proximity Read ↗

Genetic and genomic insights into male reproductive tract development.Semantic proximity Read ↗

Nine genes abundantly expressed in the epididymis are not essential for male fecundity in miceSemantic proximity Read ↗

Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive TargetsSemantic proximity Read ↗

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†Semantic proximity Read ↗

The construction of a testis transcriptional cell atlas from embryo to adult reveals various somatic cells and their molecular rolesSemantic proximity Read ↗

Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male miceSemantic proximity Read ↗

Epididymis cell atlas in a patient with a sex development disorder and a novel NR5A1 gene mutation.Semantic proximity Read ↗

MHA, an interactive website for scRNA-seq data of male genitourinary development and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.