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Transcriptomic analysis of the HPT axis in a model of oligoasthenozoospermia induced by Adenine in rats

18 Dec 2024

Abstract excerpt

Male infertility is most commonly caused by oligozoospermia, and its pathogenesis is still poorly understood at the molecular level. This study used RNA sequencing (RNA-Seq) technology to identify candidate genes and regulatory pathways that regulate semen quality in the hypothalamic, pituitary, and testicular tissues of healthy rats and Adenine-induced oligozoospermia model rats. Semen quality testing and...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 39700678
DOI: 10.1016/j.yexmp.2024.104948

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