Article

A spermatogonial perspective on the expansion of the mammalian brain

2025-09-16

Abstract excerpt

The brain and testis share many molecular similarities, yet the evolutionary implications of this overlap remain unclear. We have previously hypothesised that, throughout evolution, some genetic variants contributing to brain size expansion first arose in spermatogonia where they conferred a selective advantage to the male germline stem cells via ‘selfish spermatogonial selection’, a process analogous to oncogenes...

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Literature Corpus work: c69dbdb1-657c-55de-a08f-51d74948a24c
DOI: 10.1101/2025.09.15.676184

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