Article

Direct activation of RA signaling in cardiomyocytes protects hearts from apoptosis after myocardial infarction in mice

2020-12-04

Abstract excerpt

<h4>ABSTRACT</h4> Retinoic acid (RA) is an essential signaling molecule for cardiac development and plays a protective role in the heart after myocardial infarction (MI). In both cases, the effect of RA signaling on cardiomyocytes, the principle cell type of the heart, has been reported to be indirect. Here we have developed an inducible murine transgenic RA-reporter line using CreER T2 technology that permits l...

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Literature Corpus work: f46c6795-4f27-5c1c-8c2e-43551b4f1e52
DOI: 10.1101/2020.12.04.395970

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