Article

A general role for MIA3/TANGO1 in secretory pathway organization and function

2021-02-24

Abstract excerpt

Complex machinery is required to drive secretory cargo export from the endoplasmic reticulum, an essential process in eukaryotic cells. In vertebrates, the Mia3 gene encodes two major forms of Transport ANd Golgi Organization Protein 1 (TANGO1S and TANGO1L). Here, using genome engineering of human cells, light microscopy, secretion assays, genomics, and proteomics we show that disruption of the longer form, TANGO1...

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Literature Corpus work: f43b6730-193c-5e6c-9387-5a97e8fa048e
DOI: 10.1101/2021.02.24.432632

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