Article

Single-cell transcriptome analysis of low-dose radiotherapy-mediated alleviation of LPS-induced acute lung injury

2024-06-26

Abstract excerpt

<title>Abstract</title> <p>Background Acute lung injury (ALI), a condition with a high incidence and mortality rate worldwide, is a type of acute respiratory failure characterized by infiltrative lesions in the lungs. Low-dose radiation therapy (LDRT), which uses less than 1 Gy X-ray per session, has been tested for its clinical feasibility in suppressing lung inflammation in conditions that cause ALI. However,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f429da0e-2d04-5979-81df-f574eec2b36e
DOI: 10.21203/rs.3.rs-4508189/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptome analysis of low-dose radiotherapy-mediated alleviation of LPS-induced acute lung injuryDOI 10.21203/rs.3.rs-4508189/v1Read

A Study on the Radiosensitivity of Radiation-Induced Lung Injury at the Acute Phase Based on Single-Cell TranscriptomicsSemantic proximity Read

Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosisSemantic proximity Read

Cellular Atlas of Senescent Lineages in Radiation- or Immunotherapy-Induced Lung Injury by Single-Cell RNA-Sequencing AnalysisSemantic proximity Read

Nrf2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ARDS): Novel mechanistic considerationsSemantic proximity Read

Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosisSemantic proximity Read

Modeling radiation-induced lung injury: lessons learned from whole thorax irradiationSemantic proximity Read

The TLR9-CXCL2 Complex Orchestrates mtDNA-Driven Breg Dysfunction in Acute Lung InjurySemantic proximity Read

Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype.Semantic proximity Read

Rosmarinic Acid Alleviates Radiation-Induced Pulmonary Fibrosis by Downregulating the tRNA N7-Methylguanosine Modification-Regulated Fibroblast-to-Myofibroblast Transition Through the Exosome PathwaySemantic proximity Read

Single-cell RNA-seq reveals changes in cell subsets in the intraperitoneal lavage fluid during severe heat stroke miceSemantic proximity Read

Hemoxygenase-1 as a key mediator of acute radiation pneumonitis revealed in a human lung alveolus-on-a-chipSemantic proximity Read

Bilateral diffuse alveolar damage contributes to the fatal toxicity of pre-existing interstitial lung disease mice after partial thoracic irradiationSemantic proximity Read