Article

Biophysical characterization of high-confidence, small human proteins

2024-04-15

Abstract excerpt

Significant efforts have been made to characterize the biophysical properties of proteins. Small proteins have received less attention because their annotation has historically been less reliable. However, recent improvements in sequencing, proteomics, and bioinformatics techniques have led to the high-confidence annotation of small open reading frames (smORFs) that encode for functional proteins, producing smORF-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f41cf133-31b2-576f-9b08-cc18ccb4652f
DOI: 10.1101/2024.04.12.589296

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Biophysical characterization of high-confidence, small human proteinsDOI 10.1101/2024.04.12.589296Read

HSPBs: Small proteins with big implications in human diseaseSemantic proximity Read

Large-scale analyses of human microbiomes reveal thousands of small, novel genes and their predicted functionsSemantic proximity Read

SmProt: A Reliable Repository with Comprehensive Annotation of Small Proteins Identified from Ribosome ProfilingSemantic proximity Read

Detection of human unannotated microproteins by mass spectrometry-based proteomics: a community assessmentSemantic proximity Read

A Functional Map of the Human Intrinsically Disordered ProteomeSemantic proximity Read

The relationships between genetic diseases and the structures of protein and their interactionsSemantic proximity Read

A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseasesSemantic proximity Read

Kelch-like proteins: Physiological functions and relationships with diseasesSemantic proximity Read

Disentangling the CHAOS of intrinsic disorder in human proteinsSemantic proximity Read

Beyond the Genome: Microproteins Unveiling New Dimensions in CancerSemantic proximity Read

Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gutSemantic proximity Read

Expanding the human metaproteome: enhancing small open reading frame (smORF) prediction and ultra-deep detection of smORF-encoded proteins in the gut microbiomeSemantic proximity Read