Article

Population Frequencies Determined by Next-generation Sequencing Provide Strategies for Prospective HLA Epitope Matching for Transplantation

2020-09-16

Abstract excerpt

<title>Abstract</title> <p>Compatibility for human leukocyte antigen (HLA) genes between transplant donors and recipients improves graft survival but prospective matching is rarely performed due to the vast heterogeneity of this gene complex. To reduce complexity, we have combined next-generation sequencing and in silico mapping to determine population frequencies and matching probabilities of 150 antibody-bindin...

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Literature Corpus work: f41587d4-8b06-5bfd-b698-a60d826725c0
DOI: 10.21203/rs.3.rs-50893/v1

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