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Article

HLA-EMMA: A user-friendly tool to analyse HLA class I and class II compatibility on the amino acid level.

HLA - 1 Jul 2020

Kramer Cynthia S M, Koster Johan, Haasnoot Geert W, Roelen Dave L, Claas Frans H J, Heidt Sebastiaan

Abstract excerpt

In renal transplantation, polymorphic amino acids on mismatched donor HLA molecules can lead to the induction of de novo donor-specific antibodies (DSA), which are associated with inferior graft survival. To ultimately prevent de novo DSA formation without unnecessarily precluding transplants it is essential to define which polymorphic amino acid mismatches can actually induce an antibody response. To facilitate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32227681
DOI: 10.1111/tan.13883
PMCID: PMC7317360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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