Article
HLA Population Genetics in Solid Organ Transplantation
23 Aug 2017
Abstract excerpt
In Brief HLAs are fundamental to the adaptive immune response and play critical roles in the cellular and humoral response in solid organ transplantation. The genes encoding HLA proteins are the most polymorphic within the human genome, with thousands of different allelic variants known within the population. Application of the principles of population genetics to the HLA genes has resulted in the development of...
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