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Comprehensive nucleosome mapping of the human genome in cancer progression

2015-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Altered chromatin structure is a hallmark of cancer, and inappropriate regulation of chromatin structure may represent the origin of transformation. Important studies have mapped human nucleosome distributions genome wide, but the role of chromatin structure in cancer progression has not been addressed. We developed a MNase-Transcription Start Site Sequence Capture method (mTSS-seq) to map the n...

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Literature Corpus work
f40e3d4f-25ae-5529-8b10-d6d0395d7582
DOI
10.1101/021618
Open publication

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Comprehensive nucleosome mapping of the human genome in cancer progressionDOI 10.1101/021618
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