Article
Age Influences on the Molecular Presentation of Tumours
2020-07-08
Abstract excerpt
Cancer is often called a disease of aging. There are numerous ways in which cancer epidemiology and behaviour change with the age of the patient. The molecular bases for these relationships remain largely underexplored. To characterize them, we analyzed age-associations in the nuclear and mitochondrial somatic mutational landscape of 20,033 tumours across 35 tumour-types. Age influences both the number of mutation...
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Identifiers and source
- Literature Corpus work
- f400055e-9656-5e68-83a9-0b4cf5cc3175
- DOI
- 10.1101/2020.07.07.192237