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Article

Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis.

Journal of neuro-oncology - 1 Dec 2023

Wijaya Jeremiah H, Patel Utsav D, Quintero-Consuegra Miguel D, Aguilera-Peña Maria P, Madriñán-Navia Humberto J, Putra Aulia W, July Julius, Kataria Saurabh

Abstract excerpt

PURPOSE: The blood-brain barrier can prevent circulating tumor DNA (ctDNA) derived from the central nervous system from entering the blood making it challenging to evaluate molecular features of leptomeningeal metastasis (LM). Accordingly, we sought to systematically compare the diagnostic power or significance of ctDNA derived from cerebrospinal fluid (CSF) compared to plasma ctDNA in patients with LM. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38019327
DOI: 10.1007/s11060-023-04519-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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