Article

Panx1 Ablation Aggravates Oxidative Stress and Cell Death by Altering AMPK/mTOR signaling Pathways and the Composition of Synapses in the Zebrafish

2024-04-28

Abstract excerpt

Pannexin-1 channels have garnered attention for their implications in neurodevelopment, potentially having a dual role in mediating a delicate balance between cell death and survival. However, a comprehensive understanding of the underlying molecular and cellular mechanisms and Panx1’s potential protective functions throughout neurodevelopment remains to be determined. Zebrafish larvae with loss of Pannexin-1a fun...

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Literature Corpus work: f33756a7-3499-522f-b74a-602841e2fc2e
DOI: 10.1101/2024.04.23.590821

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