Article

A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

2017-03-31

Abstract excerpt

<h4>Background</h4> Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed that the mutation rate differs between cancer types, between patients and along the genome depending on the genetic and...

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Literature Corpus work: f3169bb2-cf1f-5b57-b75b-7c6a8c74b199
DOI: 10.1101/122879

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