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Article

A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data.

BMC bioinformatics - 19 Apr 2018

Bertl Johanna, Guo Qianyun, Juul Malene, Besenbacher Søren, Nielsen Morten Muhlig, Hornshøj Henrik, Pedersen Jakob Skou, Hobolth Asger

Abstract excerpt

BACKGROUND: Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed that the mutation rate differs between cancer types, between patients and along the genome depending on the genetic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29673314
DOI: 10.1186/s12859-018-2141-2
PMCID: PMC5909259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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