Article

GenBlosum: On Determining Whether Cancer Mutations Are Functional or Random

2025-12-15

Abstract excerpt

<title>Abstract</title> <p>Genetic mutations have proven to be the epicenters of cancer and disease progression. Traditional WXS sequencing and BLOSUM scoring can be used to infer the evolutionary conservation of amino acid substitutions, though these approaches are not informed by evolutionary variants or probable base pair sequence changes. Within gene mutation analysis, most tools focus on the probability of a...

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Literature Corpus work: 71786531-f3ef-5f53-b76d-670520939918
DOI: 10.21203/rs.3.rs-8348224/v1

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