Article

ASXL2 Mutations Are Associated with Overall Survival and Estrogen Receptor Status in TCGA-BRCA Breast Cancer Patients

2026-06-24

Abstract excerpt

Identifying mutations associated with both estrogen receptor (ER) status and patient survival may improve biomarker-based stratification in breast cancer. Here, we analyzed the TCGA-BRCA dataset to identify genes whose mutation status is linked to both ER phenotype and overall survival. In a screen of the top 20 candidate genes, most genes showed evidence for only one clinical association, whereas ASXL2 was signif...

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Literature Corpus work: f3067c51-9d00-55ee-af8e-49c1fc492502
DOI: 10.20944/preprints202606.1764.v1

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