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Article

Select gene mutations associated with survival outcomes in ER-positive ERBB2-negative early-stage invasive breast cancer: A single-institutional tissue bank study.

Cancer medicine - 1 Jul 2024

Kok Victor C, Huang To-Yu, Hsu Yi-Chiung, Chang Yuan-Ching, Yang Po-Sheng

Abstract excerpt

INTRODUCTION: The prognostic capability of targeted sequencing of primary tumors in patients with estrogen receptor-positive, human epidermal growth factor receptor-2-negative early-stage invasive breast cancer (EBC) in a real-world setting is uncertain. Therefore, we aimed to determine the correlation between a 22-gene mutational profile and long-term survival outcomes in patients with ER+/ERBB2- EBC. PATIENTS...

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Source

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Identifiers

PMID: 39031010
DOI: 10.1002/cam4.70035
PMCID: PMC11258552

Genes

ERBB2
APC
FGFR3
KIT
MAP2K4
PTEN
RB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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