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Article

Techno-Economic Assessment of Cell-Free Synthesis of Monoclonal Antibodies Using CHO Cell Extracts

2020-04-12

Abstract excerpt

Cell-free protein synthesis (CFPS) is an emerging tool for the rapid production of difficult-to-express proteins as well as for identifying protein synthesis bottlenecks. In CFPS, the biotic phase is substituted by extracts of living cells devoid of any of their own genetic material. The main advantage is that these systems delineate cell growth from recombinant protein production, enabling the expression of targe...

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Literature Corpus work
f2bc7da2-3ec0-55e5-b051-bdf6127bae38
DOI
10.3390/pr8040454
Open publication

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Techno-Economic Assessment of Cell-Free Synthesis of Monoclonal Antibodies Using CHO Cell ExtractsDOI 10.3390/pr8040454
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