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Article

Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing

22 Nov 2022

Abstract excerpt

Due to the favorable attributes of Chinese hamster ovary (CHO) cells for therapeutic proteins and antibodies biomanufacturing, companies generate proprietary cells with desirable phenotypes. One key attribute is the ability to stably express multi-gram per liter titers in chemically defined media. Cell, media, and feed diversity has limited community efforts to translate knowledge. Moreover, academic, and...

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PMID: 36411514
DOI: 10.1002/bit.28290

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