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Reexamining opportunities for therapeutic protein production in eukaryotic microorganisms

8 Jul 2017

Abstract excerpt

Antibodies are an important class of therapeutics and are predominantly produced in Chinese Hamster Ovary (CHO) cell lines. While this manufacturing platform is sufficiently productive to supply patient populations of currently approved therapies, it is unclear whether or not the current CHO platform can address two significant areas of need: affordable access to biologics for patients around the globe and...

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PMID: 28688187
DOI: 10.1002/bit.26378

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