Article

Proteomics and phosphoproteomics profiling of the co-formulation of type I and II interferons, HeberFERON, in the glioblastoma-derived cell line U-87 MG

2022-10-05

Abstract excerpt

HeberFERON is a co-formulation of Interferon (IFN)-α2b and IFN-γ in synergic proportions, with a demonstrated effect on skin cancer and other solid tumors. It has antiproliferative effects over glioblastoma multiform (GBM) clones and cell lines in culture, including U-87 MG. Omics studies in U-87 MG showed distinctive expression patterns compared to individual IFNs. Kinase signaling pathways dysregulation can also...

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Literature Corpus work: f2b7d58c-868a-5cf7-b83f-60124c07a3c0
DOI: 10.1101/2022.10.03.510562

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