Article

Levosimendan prevents tau pathology by inhibiting disulfide-linked tau oligomerization posing as a promising anti-tau therapeutics

2020-12-30

Abstract excerpt

<title>Abstract</title> <p>Tau oligomers play critical roles in tau pathology, responsible for neuronal cell death and transmitting the disease in the brain. Accordingly, preventing tau oligomerization becomes an important therapeutic strategy to treat tauopathies including Alzheimer’s disease, however progress has been slow due to difficulties of detecting tau oligomers in cellular context. Toward tau-targeted d...

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Literature Corpus work: f2ab563c-2ab3-5602-bd9f-b38b772c5d6d
DOI: 10.21203/rs.3.rs-128169/v1

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