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An essential host dietary fatty acid stimulates TcpH inhibition of TcpP proteolysis enabling virulence gene expression in <i>Vibrio cholerae</i>

2022-04-28

Abstract excerpt

Vibrio cholerae is a Gram-negative gastrointestinal pathogen responsible for the diarrheal disease cholera. Expression of key virulence factors, cholera toxin and toxin-coregulated pilus, is regulated indirectly by two single-pass membrane-localized transcription regulators (MLTR), ToxR and TcpP, that promote expression of the transcription activator toxT . TcpP abundance and activity are controlled by TcpH, a si...

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Literature Corpus work
f2738571-2ab7-5a64-b597-1782e195433e
DOI
10.1101/2022.04.28.489952
Open publication

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An essential host dietary fatty acid stimulates TcpH inhibition of TcpP proteolysis enabling virulence gene expression in <i>Vibrio cholerae</i>DOI 10.1101/2022.04.28.489952
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