ToxR regulates the production of lipoproteins and the expression of serum resistance in Vibrio cholerae.

doi:10.1073/pnas.88.5.1641

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Article

ToxR regulates the production of lipoproteins and the expression of serum resistance in Vibrio cholerae.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1991

Parsot C, Taxman E, Mekalanos J J

Abstract excerpt

The genes encoding three lipoproteins of Vibrio cholerae were identified by a combination of DNA sequence analysis and [3H]palmitate labeling of hybrid proteins encoded by TnphoA gene fusions. The expression of these three lipoproteins, TagA, AcfD, and TcpC, was controlled by ToxR, the cholera toxin transcriptional activator. The involvement of other bacterial lipoproteins in conferring resistance to the...

Topics

Amino Acid Sequence
Animals
Antibodies, Bacterial
Bacterial Outer Membrane Proteins
Bacterial Proteins
Complement System Proteins
DNA-Binding Proteins
Genotype
Guinea Pigs
Lipoproteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Palmitic Acid

Palmitic Acids

Recombinant Fusion Proteins

Transcription Factors

Vibrio cholerae

Virulence

Source

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Identifiers

PMID: 2000374
DOI: 10.1073/pnas.88.5.1641
PMCID: PMC51080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2000374-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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