Article

Strain-specific differences in <i>toxT</i> expression and virulence gene activation in <i>Vibrio cholerae</i>

2025-04-04

Abstract excerpt

The transcriptional activator ToxT is a key regulator of Vibrio cholerae virulence, controlling the expression of cholera toxin (CT) and the toxin co-regulated pilus (TCP). Insights into the regulation and function of toxT have largely come from studies on the classical biotype strain O395, which exhibits robust toxT expression. However, toxT expression is not fully consistent across V. cholerae strains. Here...

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Literature Corpus work: ce4ce420-cbd9-5a3f-ba86-46427c502080
DOI: 10.1101/2025.04.04.647171

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