Article

Sex differences in NK cells mediated by the X-linked epigenetic regulator UTX

2022-04-22

Abstract excerpt

Viral infection outcomes are sex-biased, with males generally more susceptible than females. Paradoxically, the numbers of anti-viral natural killer (NK) cells are increased in males compared to females. Using samples from mice and humans, we demonstrate that while numbers of male NK cells are increased compared to females, they display impaired production of the anti-viral cytokine IFN-γ. These sex differences we...

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Literature Corpus work: f2661801-ef90-58df-b6e9-21d4cdc14e2a
DOI: 10.1101/2022.04.21.489076

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