Article

Recombinant Adiponectin Peptide Ameliorates Cortical Neuron Damage Induced by Chronic Cerebral Hypoperfusion by Inhibiting NF-κB Signaling and Regulating Microglial Polarization

2021-01-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Chronic cerebral hypoperfusion (CCH) is common in multiple central nervous system diseases that are associated with neuronal death and cognitive impairment. Microglial activation-mediated polarization changes may be involved in CCH-induced neuronal damage. Adiponectin (APN) is a fat-derived plasma protein that affects neuroprotection. This study investigated whet...

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Literature Corpus work: f25dd9a1-9cff-58b6-8f2c-86dd4d2d652f
DOI: 10.21203/rs.3.rs-137422/v1

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