Article

Partial differentiation induction of leukemia cells co-opts NK cells to erode leukemic stemness

2026-01-16

Abstract excerpt

<title>Abstract</title> <p> ATRA-induced granulocytic differentiation of acute promyelocytic leukemia (APL) cells is thought to underpin high-rate cure of this disease. Yet, how differentiation induction affects leukemic stemness remains undetermined. To address this, we employed flow cytometry- and scRNA-seq-based leukemic subset dissection and functional assays to characterize APL hierarchy, revealing a partic...

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Literature Corpus work: f2316c39-5af1-559c-be0e-ec77f2ecb16f
DOI: 10.21203/rs.3.rs-8399393/v1

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