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Differentiation therapy of acute myeloid leukemia: past, present and future

19 Feb 2009

Abstract excerpt

PURPOSE OF REVIEW: Since the 1970s, the concept of differentiation therapy has been viewed as a promising and revolutionary approach for the treatment of acute myeloid leukemia (AML) and other cancers. However, the successful clinical application of differentiation therapy has only been realized since the late 1980s and only in one subtype of AML, acute promyelocytic leukemia (APL). The use of all-trans-retinoic...

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PMID: 19468269
DOI: 10.1097/moh.0b013e3283257aee

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