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Gain without pain: Adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector

2023-03-20

Abstract excerpt

Zika virus (ZIKV) is now in a post-pandemic period, for which the potential for re-emergence and future spread is unknown. Adding to this uncertainty is the unique capacity of ZIKV to directly transmit between humans via sexual transmission. Recently, we demonstrated that direct transmission of ZIKV between vertebrate hosts leads to rapid adaptation resulting in enhanced virulence in mice and the emergence of thre...

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Literature Corpus work
f22d6eed-370d-50a3-9d48-d6acbcf5716b
DOI
10.1101/2023.03.20.533515
Open publication

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Gain without pain: Adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vectorDOI 10.1101/2023.03.20.533515
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