Article

Engineering Cybergenetic Cell-Based Therapies

2026-01-18

Abstract excerpt

Adaptive, closed-loop control of cellular behavior is essential for next-generation therapies, yet most current treatments operate in an open-loop manner and lack robustness to patient variability and disease dynamics. Here, we establish a controltheoretic platform for rational engineering of closed-loop cell-based therapies that achieve precise and robust regulation. First, we introduce multi-dimensional nullgram...

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Literature Corpus work: f216094d-87aa-56e0-b325-225a0ddc97d0
DOI: 10.64898/2026.01.16.699922

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