Article

KICDB: A Causality-Oriented Multi-Omics Database for Kinase Inhibitor-Induced Cardiotoxicity

2025-08-24

Abstract excerpt

<h4>Background</h4> Kinase inhibitors (KIs) are mainstays of targeted cancer therapy, but their clinical utility is frequently limited by cardiotoxicity. A systematic resource to explore the underlying causal mechanisms is urgently needed. <h4>Methods</h4> We present the KICDB (Kinase Inhibitor Cardiotoxicity Database), a comprehensive and interactive web server. KICDB is built upon a framework integrating large...

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Literature Corpus work: f1fcd756-708a-5f41-be91-35cc66f18fea
DOI: 10.1101/2025.08.20.671397

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