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Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer

4 Mar 2024

Abstract excerpt

Objective: Chronic colonic inflammation seen in inflammatory bowel disease (IBD) is a risk factor for colorectal cancer (CRC). Colitis-associated cancers (CAC) are molecularly different from sporadic CRC. This study aimed to evaluate spatially defined molecular changes associated with neoplastic progression to identify mechanisms of action and potential biomarkers for prognostication. Design: IBD patients who had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38505585
DOI: 10.3389/fonc.2024.1247106

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