Back to search

Article

Simulation and Sensitivity Analysis and Cross-Validation, Demonstrating the Utility of Genteract GxE Discovery methods

2020-11-27

Abstract excerpt

Gene-environment interactions are at the heart of why many complex traits are not fully heritable, and why prediction of disease incidence and individual response to environmental changes based on genetics has been underwhelming in utility. Understanding these interactions is the primary limiting factor for the application of personalized medicine, but current methods are not well suited for dealing with complex t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f181aa8c-9faf-5673-bae9-270612cba2b7
DOI
10.1101/2020.11.25.396861
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Simulation and Sensitivity Analysis and Cross-Validation, Demonstrating the Utility of Genteract GxE Discovery methodsDOI 10.1101/2020.11.25.396861
Select a neighboring publication to make it the new centre.