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Article

Glioma genetic profiles associated with electrophysiologic hyperexcitability.

Neuro-oncology - 2 Feb 2024

Tobochnik Steven, Dorotan Maria Kristina C, Ghosh Hia S, Lapinskas Emily, Vogelzang Jayne, Reardon David A, Ligon Keith L, Bi Wenya Linda, Smirnakis Stelios M, Lee Jong Woo

Abstract excerpt

BACKGROUND: Distinct genetic alterations determine glioma aggressiveness, however, the diversity of somatic mutations contributing to peritumoral hyperexcitability and seizures over the course of the disease is uncertain. This study aimed to identify tumor somatic mutation profiles associated with clinically significant hyperexcitability. METHODS: A single center cohort of adults with WHO grades 1-4 glioma and...

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Source

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Identifiers

PMID: 37713468
DOI: 10.1093/neuonc/noad176
PMCID: PMC10836775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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