Article
Population genomics of four-dimensional cardiac motion reveals non-myocyte regulatory programmes
2025-11-23
Abstract excerpt
Genome-wide studies of cardiac structure and function have relied on global imaging metrics that fail to capture the full complexity of myocardial behaviour, leaving the genetic and environmental architecture of motion largely unexplored. Here we show, using unsupervised deep learning applied to four-dimensional cardiac imaging data in 78,113 adult participants, that latent representations of left-ventricular moti...
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Identifiers and source
- Literature Corpus work
- 8e7342b6-edd4-5b4b-acdb-9f0106b9aaad
- DOI
- 10.1101/2025.11.22.25340784